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Related Experiment Videos

The zoonotic poxviruses.

Susan Lewis-Jones1

  • 1Ninewells Hospital and Medical School, Dundee, Scotland.

Dermatology Nursing
|May 23, 2002
PubMed
Summary
This summary is machine-generated.

Animal poxviruses can cause painful skin lesions and systemic illness in humans. While typically self-limiting, these zoonotic infections often require supportive care for recovery.

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Area of Science:

  • Veterinary Medicine
  • Dermatology
  • Infectious Diseases

Background:

  • Poxviruses are a diverse group of large, double-stranded DNA viruses.
  • Zoonotic transmission of animal poxviruses to humans can occur, leading to dermatological manifestations.
  • Human infections with animal poxviruses are relatively uncommon but can present with significant morbidity.

Purpose of the Study:

  • To describe the clinical presentation and outcomes of human skin disease caused by animal poxviruses.
  • To highlight the zoonotic potential of poxviruses and their impact on human health.
  • To inform clinical management strategies for these rare infections.

Main Methods:

  • Review of clinical cases and epidemiological data.
  • Dermatopathological examination of skin lesions.

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  • Viral isolation and characterization (if applicable).

    • Main Results:

    • Animal poxviruses can induce painful blistering and crusted skin lesions (eschars) in humans.
    • Associated systemic illness may accompany the cutaneous manifestations.
    • The disease course is typically self-limiting, with a low fatality rate.

    Conclusions:

    • Human infections with animal poxviruses, though infrequent, warrant clinical recognition.
    • Supportive care is the mainstay of treatment for these zoonotic poxviral infections.
    • Understanding the clinical spectrum is crucial for accurate diagnosis and management.