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Related Experiment Videos

Inadvertent intravitreal gentamicin injection.

Z Burgansky1, T Rock, E Bartov

  • 1Department of Ophthalmology, Edith Wolfson Medical Center, Holon, Israel. b_zvia@hotmail.com

European Journal of Ophthalmology
|May 23, 2002
PubMed
Summary
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Immediate vigorous lavage of the eye following accidental gentamicin injection prevented toxic effects. This case highlights a potentially effective management strategy for such intraocular medication errors.

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Ocular Toxicology

Background:

  • Accidental intraocular injections of medications can lead to severe visual impairment.
  • Gentamicin, an aminoglycoside antibiotic, is known for its potential ocular toxicity.

Observation:

  • A 70-year-old male developed retinal detachment.
  • During vitrectomy, 20mg of gentamicin was inadvertently injected into the vitreous cavity.
  • Immediate and vigorous lavage of the vitreous cavity with balanced salt solution was performed.

Findings:

  • No signs of ocular toxicity were observed post-operatively.
  • This outcome contrasts with previously reported devastating consequences of accidental gentamicin injection.

Implications:

Related Experiment Videos

  • Prompt and thorough lavage may effectively reduce intraocular gentamicin concentration.
  • This intervention could mitigate the toxic effects and preserve visual function.
  • Highlights the importance of immediate management in accidental intraocular drug administration.