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Inadvertent intravitreal gentamicin injection.
Z Burgansky1, T Rock, E Bartov
1Department of Ophthalmology, Edith Wolfson Medical Center, Holon, Israel. b_zvia@hotmail.com
European Journal of Ophthalmology
|May 23, 2002
Summary
Immediate vigorous lavage of the eye following accidental gentamicin injection prevented toxic effects. This case highlights a potentially effective management strategy for such intraocular medication errors.
Area of Science:
- Ophthalmology
- Retinal Surgery
- Ocular Toxicology
Background:
- Accidental intraocular injections of medications can lead to severe visual impairment.
- Gentamicin, an aminoglycoside antibiotic, is known for its potential ocular toxicity.
Observation:
- A 70-year-old male developed retinal detachment.
- During vitrectomy, 20mg of gentamicin was inadvertently injected into the vitreous cavity.
- Immediate and vigorous lavage of the vitreous cavity with balanced salt solution was performed.
Findings:
- No signs of ocular toxicity were observed post-operatively.
- This outcome contrasts with previously reported devastating consequences of accidental gentamicin injection.
Implications:
- Prompt and thorough lavage may effectively reduce intraocular gentamicin concentration.
- This intervention could mitigate the toxic effects and preserve visual function.
- Highlights the importance of immediate management in accidental intraocular drug administration.