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Coronary atherosclerosis in Mangalore--a random post mortem study.

V Singh1, M R Pai, R V Coimbatore

  • 1Department of Pathology, Kasturba Medical College, Mangalore.

Indian Journal of Pathology & Microbiology
|May 25, 2002
PubMed
Summary
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Coronary artery disease is prevalent in India, with 68.59% of analyzed hearts showing atherosclerosis. Advanced stages and occlusive lesions were common, particularly in males, highlighting the need for cardiovascular disease prevention strategies.

Area of Science:

  • Cardiovascular Pathology
  • Public Health Research
  • Indian Medical Studies

Background:

  • Coronary artery disease (CAD) prevalence is increasing in India.
  • Post-mortem analysis provides crucial data on cardiovascular health.
  • Understanding CAD risk factors is vital for public health interventions.

Purpose of the Study:

  • To evaluate the prevalence of coronary artery disease (CAD) in Mangalore, India.
  • To examine the relationship between atherosclerosis, myocardial ischemia, age, and gender.
  • To identify the extent and severity of coronary atherosclerosis in the study population.

Main Methods:

  • Post-mortem examination of 70 human hearts (December 1996 - December 1997).
  • Gross and histological examination of coronary arteries and myocardium.

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  • Analysis correlated findings with age and gender of the deceased.

    • Main Results:

    • Coronary atherosclerosis was found in 68.59% of hearts (48/70).
    • Advanced atherosclerosis and occlusive lesions were prevalent, especially in males.
    • Myocardial ischemia was observed in 30% of hearts, with no correlation to stenosis severity.

    Conclusions:

    • A high prevalence of coronary atherosclerosis exists in this Indian population.
    • Males are more frequently affected by severe coronary artery disease.
    • Further research is needed to understand myocardial ischemia in relation to CAD severity.