Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The epileptic pre-aura.

E Niedermeyer1

  • 1Department of Neurology, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland, USA.

Clinical EEG (Electroencephalography)
|May 25, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The value of the EEG in diagnosis, treatmen,t and prognosis of childhood epilepsy.

Pediatric annals·2014
Same author

Alzheimer disease: primary ischemia concept and promising therapy.

La Clinica terapeutica·2009
Same author

Hippocampic theta rhythm.

Clinical EEG and neuroscience·2008
Same author

Vertebrobasilar artery insufficiency and electroencephalogram.

Clinical EEG and neuroscience·2008
Same author

Akinesia and the frontal lobe.

Clinical EEG and neuroscience·2008
Same author

Considerations of the ischemic basis and therapy of Alzheimer Disease.

Clinical EEG and neuroscience·2007
Same journal

Time distribution of seizures during long-term video-EEG monitoring.

Clinical EEG (electroencephalography)·2003
Same journal

Sequential EEG analysis during intermittent photic stimulation in never-medicated patients with schizophrenia.

Clinical EEG (electroencephalography)·2003
Same journal

Apneic seizures in infants: role of continuous EEG monitoring.

Clinical EEG (electroencephalography)·2003
Same journal

Olfactory event-related potentials in normal subjects and patients with smell disorders.

Clinical EEG (electroencephalography)·2003
Same journal

Effects of stimulus modality and response mode on the P300 event-related potential differentiation of young and elderly adults.

Clinical EEG (electroencephalography)·2003
Same journal

Focal seizures and EEG: prognostic considerations.

Clinical EEG (electroencephalography)·2003
See all related articles

Earliest pre-ictal manifestations, termed pre-auras, precede detectable seizure activity by minutes. These subtle neurological events are likely neuronal in origin and specific to focal epilepsies.

Area of Science:

  • Neurology
  • Epileptology
  • Neurophysiology

Background:

  • Pre-aura refers to the earliest pre-ictal manifestations.
  • These events are undetectable by conventional electroencephalography (EEG) and behavioral signs.
  • Recent findings suggest earliest pre-ictal vascular changes and quantified EEG alterations.

Purpose of the Study:

  • To define and characterize pre-aura phenomena in epilepsy.
  • To investigate the timing and nature of pre-aura events.
  • To determine the epilepsy types associated with pre-auras.

Main Methods:

  • Review of recent reports on pre-ictal changes.
  • Analysis of vascular changes (ischemia, hyperemia).
  • Evaluation of quantified electroencephalography (EEG) data.

Related Experiment Videos

Main Results:

  • Pre-auras can precede seizure onset by 1 to 20 minutes.
  • These phenomena are hypothesized to be neuronal, not vascular.
  • Pre-auras are likely exclusive to focal epilepsies, not generalized forms.

Conclusions:

  • Pre-auras represent a distinct phase of early seizure manifestation.
  • Neuronal activity is the probable cause of the earliest pre-aura phenomena.
  • Further research using ultrafast EEG frequency recordings is warranted.