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An All-on-chip Method for Rapid Neutrophil Chemotaxis Analysis Directly from a Drop of Blood
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A case of neutropenia with transient absence of neutrophil chemotaxis

Javed Sheikh1, Bruce J Goldberg, Michael S Kaplan

  • 1Department of Allergy & Immunology, Kaiser Permanente, Los Angeles Medical Center, California, USA. jsheikh@caregroup.harvard.edu

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|May 25, 2002
PubMed
Abstract

No abstract available in PubMed .

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Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, called chemotaxis, is essential during embryogenesis and development, immune response, tissue repair and regeneration, and reproduction. These chemical cues can either attract or repel the cell's movement. For example, axon development is determined by a combination of chemoattractants and chemorepellents that direct the growing axon towards...

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