[Drug therapy of peptic ulcer]

Though the proper genesis of peptic ulcer is still unknown, one can proceed from the fact that the cause of the development of the defect is a disturbance of the equilibrium between aggressive and defensive factors on the surface of the stomach. It is taken the view that an uncomplicated ulcus duodeni and ulcus ventriculi should be treated in the outpatient department. Strong diet prescriptions are certainly not necessary, reduction of the consumption of nicotine and avoidance of nutrients increasing secretion and individually incompatible is, however, necessary. In duodenal ulcer anticholinergic remedies and antacids are the basis of the therapy as before; other principles of treatment are only of subordinated significance. In ulcus ventriculi a reduction of quality and quantity of the gastric mucus play, perhaps, an etiologic role. Since, apart from this, a reflux of bile takes place, the derivations of the Succus liquiritiae which further the formation of mucus and the Cerucal furthering the peristalsis are to be regarded as most essential therapeutic remedies. But principle of the therapy of ulcer must always be not only to treat the diseased organ, but to try to influence therapeutically on the whole man with his conflicts which are sometimes difficult to be solved and which manifest themselves only in the gastro-intestinal tract.