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[Signet-ring-cell lymphoma. Light and electron microscopic study of gastric involvement]
Archiv Fur Geschwulstforschung
|January 1, 1986
Summary
A rare signet-ring cell lymphoma of the stomach was identified in a 73-year-old male. This malignant Non-Hodgkin lymphoma featured crystalline inclusions, mimicking signet-ring cells.
Area of Science:
- Oncology
- Gastroenterology
- Pathology
Background:
- Malignant Non-Hodgkin lymphoma can affect the stomach.
- Gastric lymphomas present with diverse histological subtypes.
Observation:
- A 73-year-old male presented with a malignant Non-Hodgkin lymphoma of the stomach.
- Histological examination revealed a follicularly growing, secondary centroblastic lymphoma.
Findings:
- Unique crystalline cytoplasmic inclusions were observed in centrocytes.
- These inclusions caused nuclear displacement, creating a signet-ring cell appearance.
- Electron microscopy identified electron-dense deposits within the rough endoplasmic reticulum.
Implications:
- This case highlights a rare presentation of gastric lymphoma.
- Understanding these crystalline inclusions is crucial for accurate histological diagnosis.
- Further research may elucidate the nature and origin of these inclusions.