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Description of six new HLA-B alleles in the 5C CREG including a B*58 intron two sequence
1Department of Oncology, Georgetown University Medical Center, Washington, DC 2007, USA.
Tissue Antigens
|May 25, 2002
Abstract:
Five of the six novel HLA-B alleles described in this report contain polymorphic motifs previously reported in HLA-B alleles, suggesting an origin resultant from a gene conversion mechanism. The sixth allele, B*35012, contains a polymorphism previously unreported in HLA-B molecules. In addition to previously reported polymorphisms, B*5806 carries a previously unreported intronic substitution in a sequencing primer annealing site.