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Updated: Aug 26, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation
Published on: September 4, 2017
Preliminary evaluation of second harmonic direct detection scheme for low-dose range in alanine/EPR dosimetry
Felipe Chen1, Carlos F O Graeff, Oswaldo Baffa
1Departamento de Física e Matemática, FFCLRP, Universidade de São Paulo, Brazil.
Abstract:
The usefulness of a direct detection scheme of the second harmonic (2h) overmodulated signal from irradiated alanine in EPR dosimetry was studied. For this purpose, a group of DL-alanine/paraffin cylindrical pellets was produced. The dosimeters were irradiated with a 60Co radiotherapy gamma source with doses of 0.05, 0.1, 0.5, 1 and 5 Gy. The EPR measurements were carried out in a VARIAN-E4 spectrometer operating in X-band with optimized parameters to obtain highest amplitude signals of both harmonics. The 2h signal was detected directly at twice the modulation frequency. In preliminary results, the 2h showed some advantages over the 1 h such as better resolution for doses below 1 Gy, better repeatability results and better linear behaviour in the dose range indicated.

