Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

TestisBank: an internet-based gene sequence database of the testis.

S Claussen1, H-U Prokosch, E Nieschlag

  • 1Institute of Reproductive Medicine of the University of Münster, Institute of Medical Informatics and Biomathematics of the University of Münster, Domagkstrasse, Münster, Germany.

International Journal of Andrology
|May 29, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sperm aneuploidy rates in younger and older men.

Human reproduction (Oxford, England)·2002
Same author

Distribution and function of FSH receptor genetic variants in normal men.

Andrologia·2002
Same author

Interpersonal testosterone transfer after topical application of a newly developed testosterone gel preparation.

Clinical endocrinology·2002
Same author

Pharmacokinetics of a new transdermal testosterone gel in gonadotrophin-suppressed normal men.

European journal of endocrinology·2002
Same author

Testosterone substitution of hypogonadal men prevents the age-dependent increases in body mass index, body fat and leptin seen in healthy ageing men: results of a cross-sectional study.

European journal of endocrinology·2002
Same author

The CAG repeat polymorphism in the androgen receptor gene affects bone density and bone metabolism in healthy males.

Clinical endocrinology·2002

TestisBank is a new database providing comprehensive gene expression data for the testis and epididymis. It aids researchers by integrating molecular and literature data for spermatogenesis studies.

Area of Science:

  • Reproductive biology
  • Bioinformatics
  • Genomics

Background:

  • The testis is transcriptionally active, with hundreds of genes involved in spermatogenesis.
  • Current resources (GenBank, MEDLINE) offer limited, unlinked data on testicular gene expression, cellular origin, and cross-tissue presence.
  • Lack of integrated data hinders detailed study of male reproductive processes.

Purpose of the Study:

  • To develop an organ-specific database, TestisBank, for comprehensive retrieval of testicular and epididymal gene expression data.
  • To provide detailed information on gene expression within specific testicular cell types.
  • To facilitate research into spermatogenesis by merging molecular and literature data.

Main Methods:

  • Generation of an organ-specific database, TestisBank.

Related Experiment Videos

  • Integration of molecular and literature data for testicular and epididymal genes.
  • Automatic updating to synchronize with genome databases.
  • Development of a user-friendly interface with relevant links.

    • Main Results:

    • TestisBank provides a more complete set of genes expressed in different testis cell types.
    • The database includes information on genes expressed in the epididymis, crucial for germ cell maturation.
    • TestisBank offers convenient access to updated information and links for male reproduction research.

    Conclusions:

    • TestisBank enhances research on spermatogenesis by offering integrated, cell-type-specific gene expression data.
    • The database serves as a model for merging molecular and literature data in organ-specific research.
    • Public availability of TestisBank (http://medweb.uni-muenster.de/TestisBank/) supports detailed insight into male reproductive biology.