Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multicomponent lifetime-based pH sensors utilizing constant-lifetime probes.

William D Bare1, Nathan H Mack, Wenying Xu

  • 1Department of Chemistry, University of Virginia, Charlottesville 22904, USA.

Analytical Chemistry
|May 30, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomembrane-Inspired Plasmonic Superstructures with Phenolic-Resin Artificial Pockets for Enantioselective Surface-Enhanced Raman Spectroscopy Detection.

ACS sensors·2026
Same author

KNOX II Transcription Factor HOS59 Regulates Gypsy Transposable Elements to Modulate Panicle Development in Rice.

Plant, cell & environment·2026
Same author

Privacy Preserving Decentralized Learning With Positive-Incentive Noise.

IEEE transactions on pattern analysis and machine intelligence·2026
Same author

Nanoparticle-Mediated Immunometabolic-Epigenetic Remodeling Enhances Schwann Cell-Macrophage Interaction for Sciatic Nerve Regeneration.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Improving the predictive validity of acute Kidney Injury after hip fracture Surgery in elderly ICU patients-A focus on "Acute Kidney Injury after hip fracture surgery among elderly patients in the ICU: incidence, risk factors and their predictive value, clinical impact-A retrospective single-center study".

Renal failure·2026
Same author

Schizophrenia and Lung Cancer: Evidence from Mendelian Randomization and Genetic Pleiotropy Analysis.

Psychiatry and clinical psychopharmacology·2026
Same journal

Machine Learning-Assisted Label-Free SERS Decoding of Mitochondrial Molecular Dynamics in Ovarian Granulosa Cells during Aging.

Analytical chemistry·2026
Same journal

Revealing the Regulatory Interplay of NHE1 mRNA and Na<sup>+</sup> in Cancer Cells Using a DNA Nanosensor.

Analytical chemistry·2026
Same journal

Towards Cellular Resolution of Tryptic Peptides in Tissue Sections by MALDI MS Imaging: A Focus on Enzyme Application and Reproducibility.

Analytical chemistry·2026
Same journal

Bioinspired Bilayer Hydrogel Colorimetric Sensor Array for Low-Temperature Food Freshness Analysis.

Analytical chemistry·2026
Same journal

Quartz Crystal Microbalance-Based Point-of-Care Testing Systems: Principles, Device Design, and Applications.

Analytical chemistry·2026
Same journal

Heterojunction Gate-Empowered OPECT Aptasensing: A Valid Protocol for Realizing High Current Gain at Low Electron Donor Dependency.

Analytical chemistry·2026
See all related articles

A novel luminescent sensor system uses constant lifetime probes to detect analytes by altering apparent sensor lifetime. This method enhances static quenching measurements and allows adjustable sensitivity through instrumental changes.

Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Sensor Technology

Background:

  • Luminescent sensors are crucial for detecting analytes.
  • Traditional methods face limitations with static quenching interactions.
  • Developing adaptable sensing systems is an ongoing challenge.

Purpose of the Study:

  • To introduce a multicomponent luminescent sensor system.
  • To enable lifetime-based measurements for static quenching sensors.
  • To provide tunable sensitivity in luminescent sensing.

Main Methods:

  • Utilizing probe species with constant intrinsic lifetimes.
  • Generating analyte-dependent changes in apparent sensor lifetime.
  • Developing a theoretical model for the multicomponent sensor.

Related Experiment Videos

  • Prototyping and measuring a pH sensor.

    • Main Results:

    • Demonstrated a new sensing scheme applicable to static quenching.
    • Showcased the ability to adjust sensor sensitivity via instrumental parameters.
    • Validated the sensor model with experimental data from a pH sensor.

    Conclusions:

    • The developed multicomponent luminescent sensor system offers a versatile approach.
    • This system expands the applicability of lifetime-based detection methods.
    • The prototype pH sensor demonstrates the practical utility of the proposed model.