[Influence of modified histones on the differentiation in vitro of chick embryo pulmonary rudiments]

The presence of carbamylated lysine-rich histones in the medium determines some evident changes on the development in vitro of the lung buds of chick embryo in comparison with the controls cultived in a standard medium or in a medium containing unmodified lysine rich histones. The action of these modified histones mainly affects the peribronchial mesenchyme.