Seminoma arising in cryptorchid testis 25 years after orchiopexy: case report

A 33-year-old man who underwent right orchiopexy at age 8 for undescended testis had a swelling develop at the same site 25 years later. He underwent right high orchiectomy. Histopathologic examination of the resected specimen suggested seminoma, and he was treated with chemotherapy (cisplatinum, etoposide, and bleomycin.) Even though the ideal age at orchiopexy is unknown, early intervention is advocated to preserve fertility and prevent malignant transformation. The management of cryptorchid testis is controversial. In view of the persistent malignant potential of this condition, early orchiopexy and lifelong follow-up are recommended.