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Related Experiment Videos

Lymphatic leishmaniasis--first case report from Nepal.

S K Sharma1, M L Das, S Rijal

  • 1BP Koirala Institute of Health Sciences, Dharan, Nepal. drsanjib@yahoo.com

The Southeast Asian Journal of Tropical Medicine and Public Health
|June 4, 2002
PubMed
Summary

This study details a rare case of lymphatic leishmaniasis in Nepal, exclusively affecting lymph nodes and presenting as generalized lymphadenopathy. Diagnosis was confirmed via cytology and serological tests, with negative bone marrow findings.

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Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Clinical Case Reports

Background:

  • Leishmaniasis is a parasitic disease with diverse clinical presentations.
  • Lymphatic involvement is a recognized but less common manifestation of leishmaniasis.
  • Geographic distribution of leishmaniasis cases provides insights into disease epidemiology.

Observation:

  • A patient presented with generalized lymphadenopathy, suggesting a systemic condition.
  • Fine needle aspiration cytology revealed Leishmania donovani bodies exclusively in lymph node aspirates.
  • Bone marrow aspiration did not show evidence of Leishmania donovani.

Findings:

  • The case was diagnosed as lymphatic leishmaniasis based on cytological and serological evidence.
  • Diagnostic confirmation included positive direct agglutination test and anti-rK39 antibodies.

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  • This represents the first reported case of lymphatic leishmaniasis in Nepal.

    • Implications:

    • Highlights the importance of considering lymphatic leishmaniasis in differential diagnoses of generalized lymphadenopathy.
    • Suggests localized lymphatic involvement as a distinct clinical form of leishmaniasis.
    • Underscores the need for expanded diagnostic awareness and surveillance of leishmaniasis in Nepal and surrounding regions.