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Related Experiment Videos

Defining and quantifying the social phenotype in autism.

Ami Klin1, Warren Jones, Robert Schultz

  • 1Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520, USA. ami.klin@yale.edu

The American Journal of Psychiatry
|June 4, 2002
PubMed
Summary

Understanding autism

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Area of Science:

  • Neuroscience
  • Autism Spectrum Disorder Research

Background:

  • Autism spectrum disorder (ASD) research necessitates better characterization of core social deficits.
  • Genetic and neurofunctional studies underscore the heterogeneity of ASD social phenotypes.

Purpose of the Study:

  • To review current methods for refining and quantifying the social phenotype in ASD.
  • To highlight novel approaches for assessing social deficits in autism.

Main Methods:

  • Literature review of existing methodologies for social phenotype assessment.
  • Exploration of eye-tracking technology for studying social visual pursuit.

Main Results:

  • Eye-tracking offers a paradigm for novel quantification of social deficits in autism.
  • This approach integrates social neuroscience branches for a synergistic research effort.

Conclusions:

  • Future advances require deeper consideration of underlying processes in experimental findings.
  • Experimental methods must better approximate naturalistic social interactions for improved ecological validity.

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