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Kyphosis in a Turner syndrome population
Deborah A Elder1, Mary Gwyn Roper, Richard C Henderson
1Division of Endocrinology, Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Pediatrics
|June 4, 2002
Summary
Kyphosis and vertebral wedging are common in girls with Turner syndrome (TS), increasing with age. Early detection through regular X-rays can help manage these spinal deformities.
Area of Science:
- Pediatric Orthopedics
- Endocrinology
- Genetics
Background:
- Turner syndrome (TS) is a genetic condition affecting females.
- Spinal deformities like kyphosis and scoliosis are potential complications in TS.
- Understanding the prevalence of these conditions is crucial for patient management.
Purpose of the Study:
- To determine the prevalence of kyphosis in girls with Turner syndrome.
- To identify associated spinal abnormalities such as vertebral wedging and scoliosis.
- To explore the relationship between these deformities and patient age.
Main Methods:
- Radiographic assessment of thoracic spine and scoliosis in 25 girls with TS (ages 5-18).
- Evaluation of standing lateral thoracic spine and anterior-posterior (A-P) scoliosis radiographs.
- Defined excessive kyphosis (>40 degrees), vertebral wedging (>5 degrees), and scoliosis (>10 degrees).
Main Results:
- 60% of patients (15/25) showed abnormal radiographic findings.
- 40% (10/25) had excessive kyphosis, and 40% (10/25) had vertebral wedging.
- Patients with kyphosis or wedging were older (13.6 years) compared to those without (10.6 years).
Conclusions:
- Increased prevalence of excessive kyphosis and vertebral wedging in girls with TS.
- These spinal deformities appear to correlate with advancing age.
- Routine radiographic screening is recommended for early detection and potential brace treatment.