Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hormonal genomics.

Chandra P Leo1, Sheau Yu Hsu, Aaron J W Hsueh

  • 1Division of Reproductive Biology, Department of Gynecology and Obstetrics, Stanford University School of Medicine, Stanford, California 94305-5317, USA.

Endocrine Reviews
|June 7, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trans-generational maintenance of mitochondrial DNA integrity in oocytes during early folliculogenesis.

PLoS genetics·2025
Same author

Hormonology: A kaleidoscopic tale of dedication, serendipity, and ingenuity.

General and comparative endocrinology·2025
Same author

Is endometriosis due to evolutionary maladaptation?

Reproductive biomedicine online·2024
Same author

Gonacin: A germ cell-derived hormone with glucogenic, orexigenic, and gonadal activities.

iScience·2023
Same author

Out of step societal and Darwinian adaptation during evolution is the cause of multiple women's health issues.

Human reproduction (Oxford, England)·2022
Same author

Spatial topological analysis of sympathetic neurovascular characteristic of acupoints in Ren meridian using advanced tissue-clearing and near infrared II imaging.

Computational and structural biotechnology journal·2021

The human genome sequence enables new biological insights, moving beyond single-gene studies to analyze entire genomes. This postgenomic approach aids in understanding hormonal signaling pathways and gene functions.

Area of Science:

  • Genomics
  • Endocrinology
  • Bioinformatics

Background:

  • The human genomic sequence provides a foundation for biological discovery.
  • Traditional endocrine research often uses a single-gene approach.
  • Genomic data allows for analysis of gene families and pathways.

Purpose of the Study:

  • To review postgenomic approaches for analyzing novel genes in hormonal signaling.
  • To highlight the importance of comparative genomics and phylogenetic studies.
  • To illustrate the shift from gene-by-gene to a global genomic perspective.

Main Methods:

  • Gene prediction from nucleotide sequences.
  • Amino acid homology analysis for gene family classification.
  • Comparative genomics and phylogenetic studies for hypothesis refinement.

Related Experiment Videos

Main Results:

  • Identification of novel genes involved in hormonal signaling.
  • Analysis of gene locations, polymorphisms, splicing variants, and expression.
  • Understanding of gene physiological functions and their roles in pathways.

Conclusions:

  • Postgenomic approaches enable a comprehensive understanding of hormonal signaling.
  • Genomic insights facilitate the study of intercellular communication and endocrine pathophysiology.
  • A community-based, global perspective is crucial for future discoveries.