Further studies on the anti-oxidative effect of putrescine in sodium nitrite-treated rats

In recent years, dietary polyamines, including putrescine, have attracted considerable interest because of the suggestion that their presence in human diet many have some anti-oxidative properties. Therefore, studies were carried out to elucidate the anti-oxidative effect(s) of oral putrescine supplementation in rats pretreated per os with either sodium nitrite or normal saline (control). Results suggest that putrescine is an effective anti-oxidant agent, which mitigates nitrite-induced lipid peroxidation in rat liver and small intestinal mucosa.