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Thrombotic microangiopathies
Daniel Halevy1, Jai Radhakrishnan, Glen Markowitz
1Division of Nephrology, Department of Medicine, Columbia-Presbyterian Medical Center, New York, NY, USA.
Critical Care Clinics
|June 11, 2002
Abstract:
The thrombotic microangiopathies (TMA) are a group of diseases associated with microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction. These seemingly disparate entities share in common a pathogenic mechanism involving endothelial injury and thrombus formation. Prognosis and treatment depend on the nature of the underlying disease.