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[Multiple keratoacanthoma centrifugum marginatum].

F Cherif1, A Mebazaa, R Kort

  • 1Service de Dermatologie, EPS La Rabta, 1007 Tunis Jabbari, Tunisie, France.

Annales De Dermatologie Et De Venereologie
|June 11, 2002
PubMed
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This study highlights a rare case of multiple, large keratoacanthoma centrifugum marginatum. Acitretine effectively treated this challenging skin condition, demonstrating retinoid efficacy.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Keratoacanthoma centrifugum marginatum is a rare keratoacanthoma variant.
  • Large lesion size and prolonged evolution present therapeutic challenges.

Observation:

  • A 63-year-old male presented with multiple keratoacanthoma centrifugum marginatum lesions on lower limbs.
  • Lesions had been evolving for six months.

Findings:

  • The patient received acitretine (1 mg/kg/day) for five months.
  • Acitretine treatment resulted in complete regression of all lesions.

Implications:

  • This case is exceptional due to lesion multiplicity and size.
  • Retinoids show efficacy in treating even severe forms of keratoacanthoma centrifugum marginatum.

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