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Updated: Aug 11, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Periodontal disease--an additional risk factor for cardiovascular diseases?]
A Klinger1, M Goldstein, A Soskolne
1Dept. of Periodontics, Hebrew University, Hadassah School of Dental Medicine, Jerusalem.
Refu'At Ha-Peh Veha-Shinayim (1993)
|June 12, 2002
Summary
A 1989 study linked coronary heart disease and periodontal disease. Subsequent research, including prospective cohort studies, explores dental infections
Area of Science:
- Periodontology and Cardiology
- Oral Health and Systemic Disease
- Infectious Disease and Atherosclerosis Pathogenesis
Context:
- A 1989 case-control study first suggested a link between coronary heart disease and periodontal disease.
- Since then, numerous studies have investigated the potential role of dental infections in atherosclerosis.
- Recent research includes prospective cohort studies examining the incidence of both conditions in large populations.
Purpose:
- To review existing literature on the association between periodontal disease and coronary heart disease.
- To explore proposed biological mechanisms linking these distinct systemic diseases.
- To synthesize current understanding of dental infections' role in atherosclerosis.
Summary:
- This article reviews studies investigating the relationship between periodontal disease and coronary heart disease.
- It examines evidence from case-control and prospective cohort studies.
- Proposed mechanisms linking oral infections to systemic atherosclerosis are discussed.
Impact:
- Highlights the growing body of evidence supporting a connection between oral health and cardiovascular health.
- Provides a foundation for understanding the complex interplay between dental infections and systemic disease.
- Informs future research directions into preventative and therapeutic strategies targeting shared risk factors.
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