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Side-effects after inhalational anaesthesia for paediatric cerebral magnetic resonance imaging
Andreas Sandner-Kiesling1, Gerhard Schwarz, Martin Vicenzi
1Department of Anaesthesiology and Intensive Care Medicine, Karl Franzens University, Graz, Austria. andreas.sandner@uni-graz.at
Insights
Post-procedure side effects are common in children after inhalational anesthesia for MRI scans. Parents should be informed about potential side effects, including neurological and abdominal symptoms, which vary by age and condition.
Area of Science:
- Pediatric Anesthesiology
- Medical Imaging
- Neurology
Background:
- Evaluating post-procedure side effects in children undergoing inhalational anesthesia for MRI.
- Assessing the type, incidence, and duration of these side effects within 72 hours.
Purpose of the Study:
- To determine the frequency and nature of side effects following inhalational anesthesia for pediatric MRI.
- To identify factors associated with specific side effects.
Main Methods:
- 112 children received inhalational anesthesia (isoflurane, sevoflurane, desflurane, or halothane) for MRI.
- Gadolinium contrast was administered in 40% of cases.
- Parental questionnaires were used to collect data on side effects.
Main Results:
- 50% of children experienced 14 different side effects within 72 hours.
- Neurological side effects were linked to age (≥5 years) and infratentorial pathology.
- Abdominal side effects, particularly nausea, were associated with age (≥5 years).
Conclusions:
- Inhalational anesthesia for pediatric MRI can lead to a variety of side effects.
- Informing parents about potential side effects is crucial.
- Side effect incidence and type necessitate parental awareness for minimally invasive procedures like MRI.
Background:
The aim of this study was to evaluate the type, incidence and duration of postprocedure side-effects in 168 children within the first 72 h after inhalational anaesthesia for magnetic resonance imaging (MRI).
Methods:
Premedication and induction followed standardized routines. Maintenance of anaesthesia was performed with inhalational anaesthetics solely: isoflurane (n=60 of 112; 53%), sevoflurane (n=32 of 112; 29%), desflurane (n=12 of 112; 11%) or halothane (n= 8 of 112; 7%) using a strapped on face mask (FiO2=0.4; flow 5 l.min-1). When indicated, gadolinium was administered (n=45; OF 112; 40%).
Results:
One hundred and twelve of 168 parents (67%) responded to questionnaires. In these 112 children, pathological MR findings were found supratentorially (n=31; 28%), infratentorially (n=9; 8%), extracerebrally (n=12; 11%) or combined (n=9; 8%). In 56 of these 112 children (50%), 14 different side-effects were reported. One hour after anaesthesia, 55 children suffered between one and four side-effects. Neurological side-effects were associated with age > or = 5 years (P < 0.01) or infratentorial pathophysiology (P < 0.01) and abdominal side-effects (P < 0.02), especially nausea (P < 0.001) with age > or = 5 years.
Conclusions:
Our findings indicate the need to inform parents of the incidence and variability of side-effects after inhalational anaesthesia for minimally invasive, diagnostic procedures, such as MRI.