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Related Experiment Videos

Audit of aminoglycosides usage.

M Ramesh1, Siby John, D Narayanappa

  • 1Department of Pharmacy Practice, JSS College of Pharmacy, Mysore, India. madhanramesh@hotmail.com

Indian Journal of Pediatrics
|June 14, 2002
PubMed
Summary

This study assessed aminoglycoside use in pediatric patients, finding appropriate usage for indication (72%) and dose (86%), but lower rates for safety (43%). Guidelines aim to improve pediatric antibiotic stewardship.

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Area of Science:

  • Pharmacology
  • Pediatric Medicine
  • Infectious Diseases

Background:

  • Aminoglycosides are crucial antibiotics in pediatric care.
  • Evaluating their appropriate use is essential for patient safety and antimicrobial stewardship.
  • Previous studies highlight variability in aminoglycoside prescribing patterns.

Purpose of the Study:

  • To evaluate the appropriateness of aminoglycoside usage in pediatric patients.
  • To identify areas for improvement in prescribing practices.
  • To assess adherence to established guidelines for aminoglycoside therapy.

Main Methods:

  • Retrospective review of pediatric patients (<12 years) receiving parenteral aminoglycosides.
  • Data collected over a six-month period at J.S.S. Hospital, Mysore.
  • Appropriateness assessed across indication, dose, duration, safety, and cost-effectiveness.

Main Results:

  • Overall appropriateness varied: indication (72%), dose (86%), duration (85%), safety (43%), cost-effectiveness (53%).
  • Gentamicin was the most frequently used aminoglycoside (53%).
  • Respiratory tract infections were the most common indication (50%).

Conclusions:

  • Judicious use of aminoglycosides is encouraged among pediatricians.
  • Implementation of aminoglycoside guidelines can enhance pediatric patient care.
  • Focus on improving safety and cost-effectiveness in aminoglycoside prescribing is needed.

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