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[Fundus changes in scleroderma (author's transl)].

I Egerer, D Fanta, H Freyler

    Klinische Monatsblatter Fur Augenheilkunde
    |October 1, 1975
    PubMed
    Summary
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    Ophthalmological examinations in scleroderma patients revealed significant fundus changes in most cases. Retinal pigment epithelium defects and vascular alterations indicate the eye is affected by this systemic collagen disorder.

    Area of Science:

    • Ophthalmology
    • Rheumatology
    • Pathology

    Background:

    • Scleroderma is a systemic autoimmune disease characterized by collagen abnormalities.
    • Ophthalmological manifestations of systemic diseases are crucial for early diagnosis and management.

    Observation:

    • Twelve patients diagnosed with scleroderma underwent comprehensive ophthalmological examinations.
    • Fundus changes were observed in nine out of the twelve patients.

    Findings:

    • Retinal pigment epithelium defects near the macula were noted in seven patients.
    • One patient exhibited a serous detachment of the retinal pigment epithelium.
    • Localized retinal vascular changes, particularly at the capillary level, were identified in three patients.

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    Implications:

    • The ocular findings suggest that collagen and vasopathological changes in scleroderma have direct counterparts within the eye.
    • These findings underscore the importance of regular ophthalmological screening for scleroderma patients.
    • Further research is warranted to elucidate the precise mechanisms and long-term consequences of these ocular alterations.