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Published on: April 24, 2020
Imbalanced Trace Elements as Risk Factors in the Pathogenesis of Glaucoma
Kira Steinhorst1, Petra Lakatos1, Bettina Hohberger1
1Augenklinik, Universitätsklinikum Erlangen, Deutschland.
Abstract:
Glaucoma, a neurodegenerative disease, is characterised by ocular pathogenic patterns, yet also by cerebral pathologies, particularly within the visual pathway. Oxidative stress is involved in glaucoma pathogenesis, similar to other neurodegenerative diseases, such as Alzheimer's disease. Trace elements can intervene within these molecular processes (e. g., via enzymes) and in the event of imbalances, also cause pathological changes. This review aims to provide an overview of the common features of glaucoma and other neurodegenerative diseases, focusing on the influence of imbalanced trace elements such as zinc, copper, iron and selenium, and oxidative stress.
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