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Seven new HLA-B alleles associated with antigens in the B7 CREG
1Departments of Oncology and Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA.
Tissue Antigens
|June 21, 2002
Abstract:
This paper describes seven novel HLA-B alleles. Five of these new alleles contain polymorphic motifs previously reported in HLA-B alleles, suggesting an origin resultant from a gene conversion mechanism. B*0723 contains a polymorphism previously unreported in class I HLA molecules. B*4105 contains a nucleotide substitution previously unreported in class I HLA molecules, which encodes a protein sequence previously reported only in HLA-C locus alleles.