Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tissue engineering of heart valves -- current aspects.

U A Stock1, J P Vacanti, J E Mayer Jr

  • 1Department of Thoracic and Cardiovascular Surgery, Friedrich-Schiller-University, Jena, Germany. ulrich.stock@med.uni-jena.de

The Thoracic and Cardiovascular Surgeon
|June 22, 2002
PubMed
Summary

Tissue-engineered heart valves aim to overcome limitations of current substitutes like anticoagulation needs. This research updates on developments, challenges, and future uses for regenerative heart valve therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Modified Calculation Improves the Accuracy of Predicted Postoperative Lung Function Values in Lung Cancer Patients.

Lung·2021
Same author

Impact of urgent coronary artery bypass grafting on acute kidney injury : A matched cohort study.

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2021
Same author

Huge thrombus attached to implantable cardioverter defibrillator line resulting in severe tricuspid inflow obstruction.

European heart journal. Cardiovascular Imaging·2019
Same author

Risk Factors Associated with In-Hospital Mortality for Patients with Acute Abdomen After Cardiac Surgery.

World journal of surgery·2019
Same author

Current clinical use of intravenous fosfomycin in ICU patients in two European countries.

Infection·2019
Same author

Risk factors associated with 30-day mortality for out-of-center ECMO support: experience from the newly launched ECMO retrieval service.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs·2019

Area of Science:

  • Regenerative Medicine
  • Biomedical Engineering
  • Cardiovascular Research

Background:

  • Current heart valve replacements have significant drawbacks, including the need for anticoagulation therapy, risk of infection, and lack of growth or self-repair capabilities.
  • These limitations drive the development of innovative solutions in cardiovascular medicine.

Purpose of the Study:

  • To provide an updated overview of the field of tissue engineering for heart valves.
  • To discuss recent advancements, persistent challenges, and prospective applications of engineered heart valves.

Main Methods:

  • Review of current literature and research findings in heart valve tissue engineering.
  • Analysis of the multidisciplinary approaches employed in designing and developing viable heart valves.

Related Experiment Videos

Main Results:

  • Significant progress has been made in creating functional tissue-engineered heart valves.
  • Key limitations still exist, including achieving full integration, long-term durability, and scalability.

Conclusions:

  • Tissue engineering offers a promising alternative to conventional heart valve substitutes.
  • Continued research and development are crucial to address current limitations and realize the full potential of regenerative heart valve therapies.