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Gender differences in irritable bowel syndrome
Heather J Chial1, Michael Camilleri
1Enteric Neuroscience Program, Gastroenterology Research Unit, Mayo Clinic and Mayo Foundation, Rochester, MN, USA.
Summary
Irritable bowel syndrome (IBS) affects many people and is common in clinics. This review examines gender differences in IBS, covering its causes, symptoms, and treatments.
Area of Science:
- Gastroenterology
- Internal Medicine
Background:
- Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disorder.
- It is characterized by abdominal pain and altered bowel habits.
- IBS significantly impacts healthcare costs, work productivity, and patient quality of life.
Purpose of the Study:
- To review and synthesize current knowledge on gender differences in IBS.
- To explore variations in epidemiology, diagnostic criteria, physiology, psychological aspects, and treatment responses between genders.
Main Methods:
- Literature review of studies investigating gender-specific aspects of IBS.
- Analysis of epidemiological data, clinical presentations, and treatment outcomes.
Main Results:
- The review highlights significant gender-based variations in IBS prevalence and symptom presentation.
- Differences in physiological mechanisms, psychological comorbidities, and treatment efficacy are observed between men and women with IBS.
Conclusions:
- Understanding gender differences is crucial for accurate IBS diagnosis and effective, personalized management.
- Further research is warranted to elucidate the underlying mechanisms driving these disparities and to optimize therapeutic strategies for all patients.