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Manufacturing and characterization of 3-d hydroxyapatite bone tissue engineering scaffolds
T-M G Chu1, S J Hollister, J W Halloran
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. ctmin@engin.umich.edu
Annals of the New York Academy of Sciences
|June 26, 2002
Abstract:
Internal architecture has a direct impact on the mechanical and biological behaviors of porous hydroxyapatite (HA) implants. However, traditional processing methods provide very minimal control in this regard. This paper reviews a novel processing technique developed in our laboratory for fabricating scaffolds with controlled internal architectures. The preliminary mechanical property and in vivo evaluation of these scaffolds are also presented.