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From lab bench to market: critical issues in tissue engineering
1Advanced Tissue Sciences, Inc., 10933 North Torrey Pines Road, La Jolla, CA 92037, USA.
Annals of the New York Academy of Sciences
|June 26, 2002
Summary
Tissue engineering innovations create biointeractive replacement tissues for repair and transplantation. These advancements offer functional and structural restoration, moving from concept to regulatory-approved products for various medical applications.
Area of Science:
- Regenerative Medicine
- Biomaterials Science
- Tissue Engineering
Background:
- Tissue engineering has evolved significantly, transitioning from theoretical concepts to practical applications.
- Innovations in tissue growth and preservation ensure product integrity, functionality, and viability from creation to end-use.
Purpose of the Study:
- To highlight revolutionary advances in tissue engineering for repair and transplantation.
- To discuss the transition of tissue engineering from research to regulatory-approved commercial products.
Main Methods:
- Development of innovative systems for tissue growth and preservation.
- Ensuring uniformity, availability, and efficacy of tissue-engineered products.
- Focus on maintaining tissue integrity, functionality, and viability throughout the product lifecycle.
Main Results:
- Tissue-engineered products are now biointeractive, providing both structure and physiological function.
- Off-the-shelf, uniform, and efficacious tissue-engineered products are available.
- Skin replacement products represent the most advanced application, with several commercialized wound care materials.
Conclusions:
- Tissue engineering offers transformative solutions for tissue repair and transplantation.
- The field holds broad potential for drug screening, genetic engineering, and organ replacement.
- Regulatory approvals and commercial availability signify the maturation of tissue engineering.