Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell cytoskeleton and tensegrity.

K Yu Volokh1, O Vilnay, M Belsky

  • 1Faculty of Civil Engineering, Technion-I.I.T, Haifa, Israel. cvolokh@aluf.technion.ac.il

Biorheology
|June 26, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measuring the displacement field inside a stressed sample.

Applied optics·2010
Same author

Cytoskeletal architecture and mechanical behavior of living cells.

Biorheology·2002
Same author

Tensegrity architecture explains linear stiffening and predicts softening of living cells.

Journal of biomechanics·2000
Same author

Color-coded duplex ultrasound compared to CT angiography for detection and quantification of carotid artery stenosis.

European journal of ultrasound : official journal of the European Federation of Societies for Ultrasound in Medicine and Biology·2000
Same author

T lymphocyte surface antigen markers in osteoporosis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·1990
Same author

Down-regulated insulin receptors in HepG2 cells have an altered intracellular itinerary.

The American journal of the medical sciences·1990
Same journal

Layer-specific residual stretch changes along the human aorta: Effects of age, gender, and circumferential quadrant.

Biorheology·2025
Same journal

The effect of particle seeding on the rheological properties of blood Analog fluid used during laser Doppler velocimetry.

Biorheology·2025
Same journal

Biomechanical changes in abdominal aortic aneurysms involve a prolonged post-failure phase.

Biorheology·2025
Same journal

Examination of hemorheological and exerkine concentrations at four-week whole body vibration exercise in obese women: A pilot study.

Biorheology·2025
Same journal

Measurement of adhesive strength between the epidermal and inner tissues of plant stems using a tensile tester.

Biorheology·2025
Same journal

Blood rheology and systemic oxidative status in patients with acromegaly.

Biorheology·2025
See all related articles

Computational studies explore tensegrity in cell cytoskeleton mechanics. Findings suggest tensegrity is likely if microtubules are straight, questioning its necessity if they are not.

Area of Science:

  • Cell biology
  • Biomechanical engineering
  • Computational modeling

Background:

  • The cytoskeleton's mechanical behavior is crucial for cell function.
  • Tensegrity, a structural principle, is hypothesized to govern cytoskeletal organization.
  • Understanding this architecture is key to cell mechanics.

Purpose of the Study:

  • To computationally investigate the role of tensegrity in cytoskeleton mechanics.
  • To compare tensegrity and non-tensegrity models under various conditions.
  • To analyze the impact of microtubule buckling on cellular mechanical properties.

Main Methods:

  • Development of plane and spatial tensegrity and non-tensegrity cytoskeleton models.
  • Inclusion of local buckling and deep postbuckling response for compressed microtubules.

Related Experiment Videos

  • Application of fully nonlinear analysis to account for large deformations.

    • Main Results:

    • Both tensegrity and non-tensegrity models showed similar linear stiffening during microtubule local buckling.
    • Microfilaments were found to be unable to sustain compression.
    • The study highlights the potential impact of microtubule straightness on tensegrity's relevance.

    Conclusions:

    • Tensegrity may not be essential if cellular microtubules are not straight.
    • The straightness of microtubules is a critical factor in determining the likelihood of tensegrity as the cytoskeletal architecture.
    • Further experimental validation is needed to confirm findings on microtubule buckling.