Process and outcome changes with relapse prevention versus 12-Step aftercare programs for substance abusers
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Updated: Sep 30, 2026

A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
Published on: March 23, 2022
Thomas G Brown1, Peter Seraganian, Jacques Tremblay
1Douglas Hospital Addiction Research Program, McGill University, Verdun, Quebec, Canada. brotho@douglas.mcgill.ca
Aims:
Presumptive support was sought for mechanisms of action whereby two conceptually distinct aftercare programs, relapse prevention (RP) and 12-Step facilitation (TSF), impact upon substance abusers.
Patients And Design:
Adults who had just completed intensive treatment were assigned randomly to either RP (n=61) or TSF (n=70) aftercare programs.
Setting:
Three residential treatment facilities.
Interventions:
Trained counselors delivered to small groups a manualized aftercare program which focused either upon the utilization of cognitive-behavioral processes to orchestrate change through an individualized treatment plan (i.e. RP) or which sought to facilitate utilization of AA's 12 Steps (i.e. TSF).
Measurements:
Process measures developed specifically to quantify either: (a) the changes in self-efficacy process in RP or (b) the utilization of AA's principles in TSF, as well as psychosocial and substance abuse indices were administered to all patients pre- and post-aftercare and at 6-month follow-up.
Findings:
A significant relationship between changes in measures of self- efficacy for RP participants as well as a trend for a relationship between process-specific change for TSF participants partially satisfied the first condition for presumptive support. The fact that the intervention-specific mediators covaried with several outcome indices, and that removal of such mediators attenuated prediction of outcome met, respectively, the second and third conditions for presumptive support.
Conclusion:
Carefully orchestrated RP and TSF aftercare programs yield process changes that are related positively to improved outcome.
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