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Related Experiment Videos

Bladder substitution in women.

A Doherty1, F Burkhard, S Holliger

  • 1Department of Urology, University Hospital Berne, Anna Seiler-Haus, CH-3010 Berne, Switzerland. fiona.burkhard@insel.ch

Current Urology Reports
|June 27, 2002
PubMed
Summary
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Orthotopic bladder substitution in women with transitional cell carcinoma (TCC) is under evaluation. Early results are encouraging for carefully selected patients, potentially preserving quality of life after cystectomy.

Area of Science:

  • Urology
  • Oncology

Background:

  • Bladder substitution in women diagnosed with transitional cell carcinoma (TCC) remains controversial.
  • Key concerns include the risk of urethral TCC involvement and potential voiding dysfunction.
  • Limited patient numbers and brief follow-up data necessitate further evaluation.

Purpose of the Study:

  • To review existing data on orthotopic bladder substitution in female patients.
  • To emphasize the risks of urethral TCC and voiding dysfunction.
  • To assess the procedure's role in improving quality of life post-cystectomy.

Main Methods:

  • Review of published data and institutional experience with orthotopic bladder substitution in women.
  • Analysis focused on outcomes related to urethral transitional cell carcinoma (TCC) and voiding function.

Related Experiment Videos

  • Evaluation of patient selection criteria and long-term quality of life.

    • Main Results:

    • Early results from multiple institutions are promising for appropriately selected female patients.
    • The risk of urethral TCC and the incidence of voiding dysfunction require careful consideration.
    • Long-term quality of life can be preserved in select cases.

    Conclusions:

    • Orthotopic bladder substitution can offer significant quality of life benefits for women undergoing cystectomy for TCC.
    • Successful outcomes depend on a functional external sphincter and clear tumor margins.
    • Further research with larger patient cohorts and longer follow-up is warranted.