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A Low-Cost Computerized System to Monitor Running Performance and Circadian Rhythms of Twenty Mice Simultaneously
Dik Van Leenen1, Agnes G. A. Bijvoet, Pim Visser
1Department of Clinical Genetics, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands; Department of Paediatrics, Sophia Children's Hospital, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands.
Abstract:
This paper describes the design and functioning of a low-cost computerized system for monitoring the voluntary activity of mice in running wheels. The required software is written in Turbo Pascal(r) and provided via the Internet (http://www.eur.nl/fgg/ch1/rodent.html). The system accommodates the simultaneous monitoring of 20 animals over a virtually unlimited period. Two applications of the system are presented; one monitors the circadian rhythm of mice, and the other tests muscle strength and endurance.