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Translational control of the embryonic cell cycle

Irina Groisman1, Mi-Young Jung, Madathia Sarkissian

  • 1Program in Molecular Medicine, University of Massachusetts Medical School, Worcester 01605, USA.

Cell
|June 28, 2002
PubMed
Summary

Regulated translation of cyclin B1 mRNA, controlled by polyadenylation, is essential for the embryonic cell cycle. This mechanism, involving CPEB and Maskin, may be a general feature of mitosis in animal cells.

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