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Advancements in the Metabolic Profiling of Three-Dimensional Brain Tumor Spheroids for Drug Screening06:50

Advancements in the Metabolic Profiling of Three-Dimensional Brain Tumor Spheroids for Drug Screening

Here, we establish a metabolic profiling platform integrating three-dimensional (3D) glioma spheroids and imaging-based normalization via extracellular flux analysis. This approach enables more accurate assessment of tumor metabolic responses to drug treatments and provides insights into potential mechanisms of...
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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Here we describe a protocol using the web-based drug repurposing hypothesis generation tool: "RE:fine Drugs." This protocol can be modified to a user's preferences at the level of the query type (gene, drug or disease) and/or the range of available advanced options.
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Future Value01:11

Future Value

The future value (FV) concept is fundamental in finance as it reflects the time value of money. It shows how a current sum of money will grow over time at a specific interest rate. This principle helps investors understand potential investment growth, making it easier to compare different financial options.
Understanding future value offers several benefits. For example, it helps in making informed investment decisions. By projecting investment growth, individuals can compare financial products...
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Future Value and Compounding01:14

Future Value and Compounding

Future value and compounding are essential concepts in finance and critical for understanding the growth of investments over time. The future value (FV) of an investment is the amount that the initial investment, known as the present value (PV), will grow to over a specified period, taking into account the effects of compounding interest. Compounding is the process where the value of an investment grows over time as the earnings from the investment generate additional earnings. This cycle of...
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Ideal Solutions02:24

Ideal Solutions

According to Raoult’s law, the partial vapor pressure of a solvent in a solution is equal or identical to the vapor pressure of the pure solvent multiplied by its mole fraction in the solution. However, Raoult's Law is only valid for ideal solutions. For a solution to be ideal, the solvent-solute interaction must be just as strong as a solvent-solvent or solute-solute interaction. This suggests that both the solute and the solvent would use the same amount of energy to escape to the...
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General Properties of Solutions02:12

General Properties of Solutions

Many common substances around us exist as a solution, such as ocean water, air, and gasoline. All solutions are mixtures of substances that are composed of varying amounts of two or more types of atoms or molecules. A mixture with a non-uniform composition is a heterogeneous mixture, whereas a mixture with a uniform composition is a homogeneous mixture. The components that make the homogeneous mixture are evenly spread out and thoroughly mixed. 
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