[Thrombophilia, venous thromboses and their treatment]

Thromboses are leading among causes of death worldwide. Arterial thromboses--the underlying cause of myocardial infarctions, strokes and acute ischemia--develop due to a defect of atherosclerotic plaque. Venous thromboses and associated venous thromboembolism killing one of 1000 world population develop in unaffected vascular wall. Recent data show that 70% cases of venous thromboembolism can be prevented by identification of thrombophilia markers--inheritable conditions associated with thromb formation. Current information on variants and prevalence of thrombophilia is given as well as recommendations on venous thromboembolism prevention.