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Prevalence of the fsr locus in Enterococcus faecalis infections
S K Pillai1, G Sakoulas, H S Gold
1Division of Infectious Diseases, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115, USA. spillai@caregroup.harvard.edu
Journal of Clinical Microbiology
|June 29, 2002
Abstract:
The fsr locus of Enterococcus faecalis confers virulence in animal models. A retrospective analysis of fsr prevalence in diverse E. faecalis clinical isolates demonstrated fsr in all endocarditis isolates versus 53% of stool isolates (P = 0.005). This supports a role for fsr-mediated virulence in the pathogenesis of enterococcal infections in humans.