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[Clinical characteristics of patients with ischemic heart failure]
1Clinica a VI-a Medicală, Spitalul Clinic de Recuparare.
Insights
Patients with ischemic heart failure are older and more likely to have cardiomyopathy than myocardial infarction. Dyspnea and higher resting heart rate are common, indicating significant systolic and diastolic dysfunction.
Area of Science:
- Cardiology
- Internal Medicine
Context:
- Coronary heart disease is a leading cause of heart failure.
- Prevalence and progression of heart failure are increasing globally.
Purpose:
- To analyze clinical characteristics, coronary risk factors, and resting hemodynamic parameters in patients with ischemic heart failure.
- To investigate differences in these parameters based on ejection fraction (EF) levels.
Summary:
- 189 ischemic heart disease patients were grouped by EF: Group A (>50%), Group B (40-49%), and Group C (<40%).
- Group C patients were older, with higher rates of ischemic cardiomyopathy, dyspnea, and cardiomegaly.
- Group C also showed greater resting heart rate, kinetic abnormalities, and diastolic dysfunction, while systolic dysfunction was universal.
Impact:
- Highlights the clinical profile of patients with varying degrees of ischemic heart failure.
- Underscores the prevalence of cardiomyopathy over myocardial infarction in advanced stages.
- Emphasizes the importance of assessing both systolic and diastolic function in managing heart failure.
Unlabelled:
A major cause of heart failure is coronary heart disease with an increasing prevalence and progression to heart failure. The objective of the study is the analysis of the clinical peculiarities, coronary risk factors and some resting hemodynamic parameters at patients with ischemic heart failure.
Methods:
There have been studied 189 patients with ischemic heart disease. The ejection fraction (EF) assessed by echocardiographic examination was used to divide them into three groups: group A of 106 with EF above 50%, group B of 55 with EF between 40-49% and group C of 28 with EF below 40%.
Results:
The mean age increased from group A (58 +/- 13 years) to group C (64 +/- 11 years, p = 0.05). Ischemic cardiomyopathy was higher at group C (32% vs 13% at group A and 24% at group B, p = 0.01) and old myocardial infarction was more frequent at group A (44% vs 45% at group B and 36% at group C, p = 0.009). Group C revealed a greater incidence of dyspnea (100%) and a greater resting heart rate (83 +/- 12/min, p = 0.03). The radiologic cardiomegaly was present at group C and at 42% at group A (p = 0.001). The echocardiographic findings show a greater prevalence of kinetic abnormalities and diastolic dysfunction at group C (p = 0.002 respectively 0.009).
Conclusion:
Patients with myocardial dysfunction are older, with a lower prevalence of myocardial infarction in contrast with a higher prevalence of cardiomyopathy. Dyspnea is the dominant symptom and the resting heart rate is higher. Systolic dysfunction is present at all patients and diastolic dysfunction at the majority. There were not differences concerning the prevalence of the coronary risk factors.
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