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Related Experiment Videos

Spinal schistosomiasis.

S Olson1, R Rossato, E Guazzo

  • 1Townsville General Hospital, Eyre Street, North Ward, Townsville, Queensland, 4810, Australia. sarahl_olson@hotmail.com

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|July 3, 2002
PubMed
Summary
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Schistosomiasis infection can cause rare neurological conditions like conus medullaris syndrome in Australia. Early empirical treatment for Schistosoma led to symptom resolution in a patient.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Tropical Medicine

Background:

  • Schistosomiasis is a parasitic disease prevalent in endemic areas.
  • Neurological complications of Schistosomiasis, such as myelopathy, are rare but serious.
  • Diagnosis can be challenging due to non-specific symptoms and negative initial investigations.

Observation:

  • A 23-year-old female presented with conus medullaris signs seven months after a positive urine test for Schistosomiasis.
  • MRI revealed an enhancing lesion in the conus medullaris.
  • Serology was positive for Schistosoma IgG and IgM, but ova and stool tests were negative.

Findings:

  • Empirical treatment for Schistosoma, without biopsy, resulted in marked symptom and sign resolution.
  • Western blot confirmed IgG positivity for Schistosoma haematobium and mansoni.

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  • The patient remained neurologically well one year post-presentation.

    • Implications:

    • Schistosoma myelopathy should be considered in the differential diagnosis of myelopathy in patients from or returning from endemic areas.
    • This case highlights the potential for neurological manifestations of Schistosomiasis even with negative parasitic investigations.
    • Early empirical treatment may be effective in managing Schistosoma-related neurological syndromes.