Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electron conformal radiotherapy using bolus and intensity modulation.

Rajat J Kudchadker1, Kenneth R Hogstrom, Adam S Garden

  • 1Department of Radiation Physics, M.D. Anderson Cancer Center, University of Texas, Houston, TX 77030, USA. rkudchad@mdanderson.org

International Journal of Radiation Oncology, Biology, Physics
|July 4, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defining a Quantitative Threshold for Adaptive Re-planning using a Percentile-based Scoring System.

International journal of particle therapy·2026
Same author

Designing an Electronic Patient-Reported Outcomes Information Infrastructure Supported by the RE-AIM Implementation Framework.

Advances in cancer education and quality improvement·2026
Same author

Proton versus photon radiotherapy for patients with oropharyngeal cancer in the USA: a multicentre, randomised, open-label, non-inferiority phase 3 trial.

Lancet (London, England)·2025
Same author

Treatment Interruption and Outcomes in Head and Neck Cancer: A Secondary Analysis of 3 Randomized Clinical Trials.

JAMA otolaryngology-- head & neck surgery·2025
Same author

Patient-reported outcomes after ipsilateral radiation therapy for N2b tonsillar squamous cell carcinoma.

Discover oncology·2025
Same author

Chemotherapy alone for stage II-IVa laryngeal squamous cell carcinoma: A 20-year follow-up.

Cancer·2025
Same journal

Single Percussive Ventilation Breath-hold Imaging and Delivery in Lung Tumor Stereotactic Ablative Radiation Therapy: Initial Observations From a Prospective Clinical Trial.

International journal of radiation oncology, biology, physics·2026
Same journal

Proton beam therapy in nonmetastatic rhabdomyosarcoma: Outcome, prognostic factors and the effect of timing of radiation therapy.

International journal of radiation oncology, biology, physics·2026
Same journal

Hypofractionated Proton Reirradiation for Recurrent Glioblastoma: Clinical and Dosimetric Outcomes from a Large Single Institution Series.

International journal of radiation oncology, biology, physics·2026
Same journal

Gastrointestinal Motility-Induced Interplay in Pancreas Proton Therapy: Motion Simulation and Dosimetric Impact.

International journal of radiation oncology, biology, physics·2026
Same journal

Intra-fractional Voxel-wise Anatomical Motion Tracking Guided by Multimodal Respiratory Surrogates in Radiotherapy: Framework Development and Multi-Center Validation.

International journal of radiation oncology, biology, physics·2026
Same journal

A Gaussian-based planning approach for robust dose-escalated stereotactic body proton therapy.

International journal of radiation oncology, biology, physics·2026
See all related articles

Intensity-modulated electron beams significantly improve dose homogeneity in conformal electron beam therapy using shaped bolus. This technique reduces dose spread in the planning target volume (PTV), enhancing treatment precision for various cancers.

Area of Science:

  • Radiation oncology
  • Medical physics

Background:

  • Conformal electron beam therapy with shaped bolus can conform the 90% isodose surface to the planning target volume's (PTV) distal surface.
  • Irregular bolus surfaces increase PTV dose heterogeneity from 10% to approximately 20%.

Observation:

  • This study evaluated the impact of varying incident electron intensity on dose homogeneity.
  • Three patients with chest wall, thorax, and head-and-neck cancer were analyzed.

Findings:

  • Intensity modulation reduced the DeltaD(90%-10%) for the PTV across all cases.
  • For instance, the head-and-neck case saw a reduction from 14.9% to 9.2%.

Implications:

  • Intensity-modulated electron beams offer a significant improvement in PTV dose homogeneity.

Related Experiment Videos

  • This advancement enhances treatment precision for patients undergoing conformal electron beam therapy with shaped bolus.