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Cognitive function in elderly people is influenced by vitamin E status.

Rosa M Ortega1, Ana M Requejo, Ana M López-Sobaler

  • 1Departamento de Nutrición, Facultad de Farmacia, Universidad Complutense de Madrid, Spain. rortega@farm.ucm.es

The Journal of Nutrition
|July 5, 2002
PubMed
Summary

Elderly individuals with lower vitamin E intake showed poorer cognitive performance. Improving vitamin E status may enhance cognitive function in older adults.

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Cognitive Neuroscience

Background:

  • Cognitive decline is a significant concern in the elderly population.
  • Vitamin E, a potent antioxidant, plays a role in neurological health.
  • Understanding the link between vitamin E status and cognition is crucial for preventative strategies.

Purpose of the Study:

  • To investigate the association between vitamin E status and cognitive performance in older adults.
  • To determine if dietary intake and serum levels of vitamin E correlate with cognitive test results.

Main Methods:

  • A cohort of 120 elderly individuals (65-91 years) with no cognitive impairment was studied.
  • Dietary vitamin E intake was assessed via weighed food records.
  • Serum alpha-tocopherol levels and cognitive function using the Pfeiffer's Mental Status Questionnaire (PMSQ) were measured.

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Main Results:

  • Participants with vitamin E intake below 50% of recommendations had significantly higher PMSQ error scores.
  • Higher serum alpha-tocopherol concentrations and alpha-tocopherol/cholesterol ratios were observed in subjects with no PMSQ errors.
  • These findings indicate a positive correlation between vitamin E status and cognitive function.

Conclusions:

  • Vitamin E status is associated with cognitive performance in the elderly.
  • Maintaining adequate vitamin E levels may support cognitive health in aging populations.
  • Interventions to improve vitamin E status could be beneficial for elderly cognitive function.