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Updated: Sep 30, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Diagnostic value of d-dimer in patients with a moderate pretest probability of deep venous thrombosis
Carlos Aguilar1, Angela Martinez, Angel Martinez
1Department of Haematology, Hospital General de Soria, Soria, Spain. caraguilar@excite.com
Abstract:
The negative predictive value (NPV) of d-dimer (DD) for the exclusion of venous thromboembolism is, overall, high and tends to increase as clinical pretest probability decreases. We have assessed the accuracy of a diagnostic protocol including clinical evaluation and DD in 134 outpatients presenting with a moderate pretest probability of proximal deep venous thrombosis (DVT). In these patients, a negative DD value safely excluded DVT (NPV 100%, 95% CI 85-100) In our experience, these results are equivalent to those found for low-pretest probability patients and therefore the same diagnostic strategy can be used for both risk groups.
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