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Subcutaneous Administration of Muscarinic Antagonists and Triple-Immunostaining of the Levator Auris Longus Muscle in Mice
07:09

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Clinical use of cholinomimetic agents: a review

Philip J Blount1, Conner D Nguyen, James T McDeavitt

  • 1Charlotte Institute of Rehabilitation, 1100 Blythe Boulevard, Charlotte, NC 28203, USA.

The Journal of Head Trauma Rehabilitation
|July 11, 2002
PubMed
Abstract

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Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
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