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Updated: Aug 14, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
Published on: June 30, 2018
[Primary glomerulopathies: incidence, dynamics and clinical manifestations of morphological variants]
B R Dzhanaliev1, V A Varshavskiĭ, A A Laurinavichus
1I.M. Sechenov Moscow Medical Academy, 119881, Moscow.
Abstract:
4400 biopsies studied in the pathology department of I.M. Sechenov Moscow Medical Academy in 1970-1999 were analysed. Primary glomerulopathy (PGP) was found in 62.4% of nephrobiopsies. PGP was represented by mesangioproliferative glomerulonephritis (MPGN, 48.9%), mesangiocapillary glomerulonephritis (MCGN, 18.4%), membranous nephropathy (MN, 13.4%), focal segmentary glomerulosclerosis/hyalinosis (FSGH, 7.8%), minimal changes (MC, 5.6%). Mainly of nephrotic origin were MC, MN, FSGH. The hematuric form was primarily represented by MPGN. In 1970-1999, the share of non-inflammatory variants (MC, MN, FSGN) was increasing while hematuric variants (MPGN, MCGN) had the tendency to a decrease in their relative frequency.
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