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[Interleukin 12 (IL-12) and its receptor]
Jacek Szeliga1, Teresa Gościcka
1Katedra Immunologii Instytutu Mikrobiologii i Immunologii Uniwersytetu Łódzkiego. szelj@biol.uni.lodz.pl
This article reviews of recent data on the structure of IL-12 and the function of its receptor (IL-12R). It presents a new opinion on the role of its subunits in the cytokine activity and on the signal transmission via IL-12R in the process of cell activation by IL-12.
This article reviews of recent data on the structure of IL-12 and the function of its receptor (IL-12R). It presents a new opinion on the role of its subunits in the cytokine activity and on the signal transmission via IL-12R in the process of cell activation by IL-12.