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The membrane suppressor: a historical perspective.

Timothy S Stevens1

  • 1stevptm@earthlink.net

Journal of Chromatography. A
|July 11, 2002
PubMed
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The membrane suppressor for ion chromatography, developed in 1971, faced delays but was improved by 1981. A packed membrane suppressor resolved band broadening issues by 1982, enhancing chromatography performance.

Area of Science:

  • Analytical Chemistry
  • Chromatographic Techniques

Background:

  • The membrane suppressor for ion chromatography was first introduced in 1971.
  • Development was initially hindered by the availability and durability of suppressor columns.

Purpose of the Study:

  • To detail the historical development and technical challenges of membrane suppressors in ion chromatography.
  • To highlight the innovations that overcame limitations in early membrane suppressor designs.

Main Methods:

  • Review of historical development milestones for membrane suppressors in ion chromatography.
  • Analysis of technical challenges, including band broadening, associated with early suppressor designs.

Main Results:

  • A practical membrane suppressor was developed by 1981, but exhibited significant band broadening.

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  • The introduction of the packed membrane suppressor in 1982 effectively addressed the band broadening issue.

    • Conclusions:

    • The evolution of membrane suppressors, particularly the packed design, was crucial for advancing ion chromatography.
    • Overcoming technical limitations like band broadening enabled compatibility with modern, high-performance chromatographic columns.