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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

[Skin manifestations in kidney diseases]

P Häusermann1

  • 1Dermatologische Universitätsklinik, Kantonsspital Basel. phaeusermann@uhbs.ch

Praxis
|July 12, 2002
PubMed

Insights

Skin and kidney disorders often share specific symptoms, making integument examination crucial for diagnosing internal organ pathology. This study details hereditary and acquired diseases affecting both skin and kidneys, focusing on chronic renal failure manifestations.

Area of Science:

  • Dermatology
  • Nephrology
  • Pathophysiology

Context:

  • Skin manifestations are frequently observed in patients with renal disorders.
  • Cutaneous signs can indicate underlying internal organ pathology.
  • Understanding these connections is vital for comprehensive patient assessment.

Purpose:

  • To highlight the specific relationship between skin irritations and renal disorders.
  • To present hereditary syndromes and acquired diseases with shared skin and kidney symptoms.
  • To emphasize skin alterations in chronic renal failure, focusing on pathophysiology.

Summary:

  • This review examines the specific and unspecific skin alterations associated with chronic renal failure.
  • It includes a selection of hereditary syndromes and acquired diseases affecting both the skin and kidneys.
  • The focus is on macroscopic and microscopic skin changes and their pathophysiologic mechanisms, rather than therapeutic options.

Impact:

  • Provides a diagnostic aid by linking integument changes to internal organ pathology.
  • Enhances understanding of dermatological manifestations in nephrology patients.
  • Offers insights into the pathophysiologic mechanisms of skin alterations in chronic kidney disease.

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