Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multishot 3D slice-select tailored RF pulses for MRI.

V Andrew Stenger1, Fernando E Boada, Douglas C Noll

  • 1University of Pittsburgh Department of Radiology and Bioengineering, Pittsburgh, Pennsylvania 15213, USA. stengerva@msx.upmc.edu

Magnetic Resonance in Medicine
|July 12, 2002
PubMed
Summary

This study introduces a multishot 3D tailored RF pulse method for high-resolution MRI slice excitation. The technique enables reduced susceptibility artifacts in functional MRI (fMRI) at 3 Tesla.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A vendor-neutral functional MRI acquisition protocol for multi-site studies.

Aperture neuro·2026
Same author

Single-Shot 2D Radial Echo Planar Imaging for Functional MRI.

Magnetic resonance in medicine·2026
Same author

Spatiotemporal Maps for Dynamic MRI Reconstruction.

IEEE transactions on computational imaging·2026
Same author

Progressive axonal degeneration in white matter pathways traversing peritumoral penumbra in frontotemporal glioma.

Computational diffusion MRI. CDMRI (Workshop)·2026
Same author

Clinically Feasible White Matter Fiber Tractography in Peritumoral Zones With Cerebral Vasogenic Edema.

Magnetic resonance in medicine·2026
Same author

Quantum Sensing MRI for Noninvasive Detection of Neuronal Electrical Activity in Human Brains.

ArXiv·2026

Area of Science:

  • Magnetic Resonance Imaging
  • Pulse Sequence Design
  • Functional Neuroimaging

Background:

  • Conventional MRI pulse sequences struggle to achieve high resolution for thin slices, limiting functional MRI (fMRI) applications.
  • Intravoxel dephasing artifacts caused by magnetic susceptibility variations degrade image quality in specific brain regions.
  • Existing methods often require long radiofrequency (RF) pulses, posing practical challenges for rapid imaging.

Purpose of the Study:

  • To present a novel multishot 3D slice-select tailored RF pulse method for arbitrary resolution slice excitation.
  • To overcome the limitations of long RF pulse durations for exciting thin slices with adequate resolution.
  • To reduce susceptibility artifacts in T*(2)-weighted fMRI, particularly in challenging brain areas.

Main Methods:

Related Experiment Videos

  • The method decomposes small tip angle tailored RF pulses into separate excitations based on linearity.
  • Individual excitations are complex summed to create the final image.
  • Simulations, phantom experiments, and human brain imaging at 3 Tesla were performed.

Main Results:

  • The technique allows for the excitation of slice profiles with arbitrary resolution.
  • A 5 mm-thick slice in the human brain was successfully excited with reduced susceptibility artifacts.
  • At most four shots of 40 ms pulse length were sufficient for excitation at 3T.

Conclusions:

  • The multishot 3D tailored RF pulse method offers a practical solution for high-resolution slice excitation in MRI.
  • This technique significantly reduces susceptibility artifacts, improving fMRI utility in susceptible brain regions.
  • The method demonstrates efficient performance with short pulse durations, enabling advanced neuroimaging applications.